The character will no longer be known as Peter Parker – but will become the young Pavitr Prabhakar.
He will also have a more modest costume, wearing a dhoti, the loincloth worn by men in India.
Spider-Man would become an Indian boy in Mumbai and dealing with local problems and challenges, he added.
Spider-Man India will interweave local customs, culture and mystery to make it more relevant to the readers, set against the backdrop of monuments including the Taj Mahal and the Gateway of India.
The Green Goblin villain will be replaced by Rakshasa, an Indian mythological demon that has shape-shifting abilities.