This is not exactly my view, but Robin Hanson is always worth reading:
The next big change is likely whole brain emulations (i.e., ems), within a century or so. Profit-seeking investors may make trillions of copies of dozens of most suitable humans, and further select among trillions of ways to tweak each em. This will allow enormous selection for the most adaptive em minds. Adaptive behavior in the early em era has high work coordination, accepts more alien bodies and environments, has little interest in kids or hyper-stimuli, and accepts death, high trainee failure rates, long work hours, and near-subsistence wages. Some of this may be achieved via genuine preference changes, but initially most will be achieved via strong delusory self-control.
There is much more in the post.