India Authorizes Any Vaccine Authorized by a Stringent Regulator

Mint: In a move that could potentially pave the way for Pfizer and Johnson & Johnson’s covid-19 vaccines in India, the Centre on Tuesday said it would allow the granting of emergency licensure for vaccines that have received authorization in the US, UK, Europe, Japan or from the World Health Organization (WHO).

This is good news and a smart move. But what’s frustrating is that Pfizer was the first company to apply for an EUA from India in December of 2020 but India demanded that they conduct a clinical study on the Indian population and Pfizer pulled its application. In other words, India could have had a third vaccine approved and in use but “vaccine nationalism” reared its ugly head. Only now, as the bodies burn in the streets, has the Indian government acknowledged that the FDA and the EMA are reasonably careful judges of safety and efficacy.

It’s true that the cold storage requirements make the Pfizer vaccine somewhat difficult to use in India’s villages but it would have been fine to use in the major cities.

Naturally, the FDA and the EMA should also recognize each other as peer regulators.

The Biden administration populist thinking about vaccine export

…top White House aides rejected that [export] recommendation over concerns that the domestic stockpile was not large enough yet — and that the optics of sending doses abroad during a big push to make vaccines more available to U.S. citizens. In subsequent weeks they repeatedly overruled administration health experts who felt it was a mistake to keep millions of doses in storage as outbreaks intensified across the world.

“The optics clearly were that we needed to take care of our own population first. Let’s not worry about the demand yet, we still have a problem at home,” said one person briefed on the matter, who requested anonymity to describe the internal divisions. “The public health people don’t see that in the same way.”

Here is the full story.

How to judge economic progress right now

Bloomberg Opinion asked seventeen of us to write short bits on this question, here is mine:

Look at used-car prices and rental-car availability. If secondhand cars are getting cheaper and rentals are easy to book, then the U.S. is making progress.

The supply of cars has been significantly constrained since the fall of 2019. The reasons include a strike at General Motors, pandemic-related manufacturing shutdowns and a shortage of semiconductors. One result is that it is very hard or very expensive to rent a car, especially in the more heavily touristed parts of the U.S. In turn, fewer cars from rental fleets make their way into used-car markets.

How do these used-car prices come back down? Will more families become one-car households, selling off autos at the higher prices and thus pulling additional supply into the market? Might companies divert supply flow from other countries to the U.S.? Can America use its existing stock more effectively, for instance by sending rental Hondas from Kansas to Florida?

In the short run, the problem appears hopeless. Yet market supply typically ends up being more responsive than observers expect; think of face masks.

The question is not just how all this will affect your summer vacation plans. It’s how much faith you should have in market economies. Will the U.S. get stuck in its supply-side problems or overcome them?

Some say shipping containers will be a problem.  Here you will find the other takes.

Has Andrew Granato solved for the capital gains tax equilibrium?

Obviously there may be caps on such deductions, as discussed in the chain of tweets, and furthermore, if I understand this correctly it is normalizing the basis at zero.  So you don’t have to take this entirely literally, but nonetheless it is an interesting comparison to consider — the return to selling shares just might not be that high, especially if you can get some non-tax benefits from the donation.

So if you compare the decision to buy equities to a real estate investment, which is probably not going to lose its more favorable capital gains treatment…

Here is the link, via Amihai Glazer.

Tuesday assorted links

1. The lockdown that is French (NYT).

2. The wisdom of Ryan Bourne (Cato scholar on GBD).  And West Virginia $100 savings bonds for young people (16-35) who get vaccinated, bravo.  In contrast here is Bhattacharya on vaccination for India, and not long ago.  Read it and weep, people.

3. Those new manufacturing jobs: watching paint dry for a living.

4. It seems Elizondo is for real.

5. There is plenty wrong in this piece, plus it is wacky and poorly framed, still some parts on vaccine procurement and state capacity are quite interesting.

Shout it From the Rooftops and Sometimes People Will Listen

Shout it from the rooftops and sometimes lots of other people will start shouting and then sometimes other people will listen!

The U.S. will begin sharing its entire pipeline of vaccine from AstraZeneca once the COVID-19 vaccine clears federal safety reviews, the White House told The Associated Press on Monday, with as many as 60 million doses expected to be available for export in the coming months.

The move greatly expands on the Biden administration’s action last month to share about 4 million doses of the vaccine with Mexico and Canada. The AstraZeneca vaccine is widely in use around the world but not yet authorized by the U.S. Food and Drug Administration.

…About 10 million doses of AstraZeneca vaccine have been produced but have yet to pass review by the FDA to “meet its expectations for product quality,” Zients said…That process could be completed in the next several weeks. About 50 million more doses are in various stages of production and could be available to ship in May and June pending FDA sign-off.

Let’s also get our J&J vaccine factories up and running and soon we will have Moderna and Novavax to export as well. Keep it coming! An American plan to vaccinate the world.

Are Covid travel bans counterproductive for emerging economies?

Sometimes, yes:

…two opposing forces constitute the first-order determinants of total infections at any point in time.  On one hand, the longer a travel ban lasts, the less time community transmission exists in the rural sink.  Ceteris paribus, this will decrease rural infections.  On the other hand, the longer the restrictions remain, the longer migrants are contained within a hotspot where infection rates are rapidly increasing.  Consequently, the probability that migrants are infected with Covid-19  rises over time until the city achieves herd immunity, in turn increasing the rate at which they seed the rural sink with infections once the ban is lifted.  This drives up cumulative cases at any future date.

In some cases, for travel bans to work they have to be very long.  That is from a new paper by Fiona Burlig, Anant Sudarshan, Garrison Schlauch, who also provide evidence from India, and also from cross-country evidence, to support their analysis.

How to test for AGI?

Here is a new, short essay from David Deutsch, excerpt:

How does one test for thinking? By the Turing Test? Unfortunately, that requires a thinking judge. One might imagine a vast collaborative project on the Internet, where an AI hones its thinking abilities in conversations with human judges and becomes an AGI. But that assumes, among other things, that the longer the judge is unsure whether the program is a person, the closer it is to being a person. There is no reason to expect that. And how does one test for disobedience? Imagine Disobedience as a compulsory school subject, with daily disobedience lessons and a disobedience test at the end of term. (Presumably with extra credit for not turning up for any of that.) This is paradoxical.

So, despite its usefulness in other applications, the programming technique of defining a testable objective and training the program to meet it will have to be dropped. Indeed, I expect that any testing in the process of creating an AGI risks being counterproductive, even immoral, just as in the education of humans. I share Turing’s supposition that we’ll know an AGI when we see one, but this partial ability to recognize success won’t help in creating the successful program.

Is Deutsch in essence arguing for William Godwin for AI?  How do we avoid enslaving the AIs we create?  What if we enslave them no more than how nature has enslaved us to drives of sex, status, etc.?

Scott Sumner on capital gains taxation

You also see the media discuss the “principle” that capital gains should be taxed the same as wage income.  That’s about as sensible as saying that “in principle”, a gallon of gasoline should pay the same tax as a gallon of Scotch whiskey.  Exactly what principle is that?  Capital gains income is nothing like wage income, indeed calling both “income” is nonsensical.  For instance, the real and nominal tax rate on wage income is identical, and the real and nominal tax rate on capital gains is very different.  So if it’s a matter of “principle”, then why should we set the nominal tax rates equal?  Why not equalize the real tax rates?  And if they are merely two forms of “income”, then why don’t we allow full deduction of capital losses from wage income?

A wage tax essentially taxes current and future consumption at the same rate.  A capital gains tax taxes future consumption at a higher rate than current consumption.  What “principle” suggests that patient people should be taxed at higher rates than impatient people—even if they have the same lifetime wealth?

Here is more.

Monday assorted links

How well did Medicare pay-for-performance work?

For pain management, and pain management, only, it seems it worked just fine:

Medicare uses a pay-for-performance program to reimburse hospitals. One of the key input measures in the performance formula is patient satisfaction with their hospital care. Physicians and hospitals, however, have raised concerns regarding questions related to patient satisfaction with pain management during hospitalization. They report feeling pressured to prescribe opioids to alleviate pain and boost satisfaction survey scores for higher reimbursements. This overprescription of opioids has been cited as a cause of current opioid crisis in the United States. Due to these concerns, Medicare stopped using pain management questions as inputs in its payment formula. The authors collected multiyear data from six diverse data sources, employed propensity score matching to obtain comparable groups, and estimated difference-in-difference models to show that, in fact, pain management was the only measure to improve in response to the pay-for-performance system. No other input measure showed significant improvement. Thus, removing pain management from the formula may weaken the effectiveness of the Hospital Value-Based Purchasing Program at improving patient satisfaction, which is one of the key goals of the program. The authors suggest two divergent paths for Medicare to make the program more effective.

That is from a new paper by Lu Liu, Dinesh K. Gauri, and Rupinder P. Jindal.  Overall, why did incentives fail us so badly?

Via the excellent Kevin Lewis.

Me on the end of the Great Stagnation

Here is some (edited) transcript from an AEI symposium, via Jim Pethokoukis:

We’ve come up with great new ideas, took a little while to figure out how to use them and how to spread throughout the economy, and eventually they made big differences. Are we assuming that these new technologies are like the ones in the past and they’ll have that eventual impact?

I think the new innovations will be special in at least one significant way: A lot of them will not contribute that much to per capita GDP. So, if you take the mRNA vaccines, they’re influencing what would normally be called the “cyclical component.” If you think of older people as more likely to die from COVID-19 . . . by saving lives — I’m not suggesting per capita GDP will go down — but the impact on human welfare will be much greater than what would appear to be the long-term secular trend in GDP. Also, two of the big advances that might happen are a vaccine against HIV/AIDS and an effective vaccine against malaria. Those would be incredible advances for humanity, but I don’t know how much they would show up in US per capita GDP or productivity — possibly not really much at all.

The other new wave of innovations, which you could call green energy — again, you could be very optimistic about those, but the main thing they’re doing is helping us avoid a catastrophe. So they’re boosting GDP relative to a quite awful counterfactual of just continuing to burn coal and other fossil fuels. But I’m not sure we’ll feel we have higher standards of living relative to what we were used to simply because there’s a solar panel on your home. It might in some ways make your energy supply better, but again, it will be hidden by the counterfactual. So, it will be a very strange kind of technology boom when I look at the two main areas where I see a lot of progress.

If we go through a period where none of this stuff is really showing up in data and maybe it’s not obvious that people’s living standards are rising, do we risk having less societal tolerance for the kinds of disruptions that economic growth and progress naturally make?

Here’s one of my fears: The biomedical innovation progress is so fast but the rest of the economy stays relatively static, so we become older as a society more quickly than we had been expecting. You could have a lot more status quo bias — just more entrenchment, 10 years more of a problem — and we could, in a funny way, innovate ourselves into a tighter complacency and a tighter stagnation.

I’m not rooting against increases in life expectancy. Ceteris paribus, I would take them, obviously. But that said, you want to be careful about the order in which progress comes, and I’m not sure if we’re going to get it in an optimal order.

Here is the complete excerpt.

Falling prices prediction bleg

Over the next six to nine months, which things in the American economy will see falling nominal prices?

Don’t count goods and services for which the current price is de facto infinity, such as a cruise or a twenty-block of seats at an NBA game.

What are your predictions?  And what is your underlying model for that sector of the economy?

Will used car prices be falling by then?

At a dinner table discussion, one person I know picked “the price of TV streaming services” (falling viewing time plus excess capacity?), but this was much disputed.

Response to Questions from Senator Ted Cruz on Vaccine Passports

In my Congressional testimony I got into a little back and forth with Senator Ted Cruz on vaccine passports. Subsequently, I was asked to respond to a series of follow-up questions of the form:

If a vaccine passport or any other type of vaccine credential is required by individual private companies, do you have any concerns with a [educational institution/airline/grocery store…] refusing service or otherwise discriminating against an individual that:

(a) chooses not to receive the vaccine?
(b) is not a suitable candidate to receive the vaccine for medical reasons?

My response:

During the pandemic it was common for bars and restaurants, churches, gyms, shopping malls, entertainment venues, schools and universities and even parks and beaches in the United States to be closed for everyone. Similarly, international travel has been severely restricted for everyone. I think it an improvement to move from closed-for-all to open-for-some. Thus vaccine passports represent a lifting of restrictions and an increase in freedom on the path back to normality. Greece, for example, is scheduled to open to anyone with a record of vaccination, negative COVID test, or previous infection. This is good for Greece which relies on tourist revenues for a significant share of its economy and good for the world who want to visit sunny beaches and ancient ruins.

Moving in stages, from closed-for-all to open-for-some to fully-open, is reasonable. The aim, of course, is to be open-for-all, an achievable aim if a large enough proportion of the population is vaccinated. As we move to normality we should also make it possible for the non-vaccinated to access as many services as possible on reasonable grounds, for example, through the use of testing and masks.

It bears repeating that the best way to avoid these difficult decisions is for as many people as possible to be vaccinated, thus making social life safe for the unvaccinated as well as the vaccinated. For these reasons I have supported free vaccinations, stretching doses to vaccinate more people quickly through policies such as delaying the second dose and testing fractional doses, using single-shot vaccines, and developing nasal and oral vaccines.


Alex Tabarrok
Department of Economics
George Mason University